Vapreotide

Also known as: RC-160 · Sanvar

Not FDA-approved

Last verified: October 30, 2026

At a glance

FDA approval Not FDA-approved No record in Drugs@FDA
Randomized controlled trials 4 of 237 publications on PubMed
Registered clinical trials 2 0 active
Adverse event reports 1 0 classified as serious
  • Vapreotide is not an FDA-approved drug: Drugs@FDA has no record of it.
  • PubMed lists 237 publications mentioning it, including 4 randomized controlled trials and 79 animal-only studies.
  • ClinicalTrials.gov lists 2 registered studies testing it (0 active).
  • FDA's adverse event system (FAERS) holds 1 report mentioning it; 0 classified as serious. Reports do not prove causation.

Research topics

  • Somatostatin 163
  • Receptors, Somatostatin 76
  • Antineoplastic Agents 54
  • Tumor Cells, Cultured 38
  • Octreotide 35
  • Cell Division 34
  • Pancreatic Neoplasms 20
  • Cricetinae 18
  • Neoplasms 18
  • Prostatic Neoplasms 17

Most frequent MeSH subject headings in the latest PubMed records (English, as indexed).

Regulatory status

Drugs@FDA applications

No application found in Drugs@FDA, FDA's database of approved drugs.

Source: Drugs@FDA (openFDA) · verified October 30, 2026 · API query

FDA compounding safety list

Not on FDA's list of bulk drug substances that may present significant safety risks in compounding.

Source: FDA.gov — Category 2 bulk drug substances · verified October 30, 2026

Removal of a substance from a regulatory list does not mean it has been approved. A "research use only" label does not make a product safe or legal for human use.

Scientific publications

  • All publications 237
  • Human (MeSH) 134
  • Animal only 79
  • Clinical trials 8
  • Randomized controlled trials 4
  • Systematic reviews & meta-analyses 6
  • Case reports 2
  • Retracted 0

Counts are PubMed records that mention the peptide in the title or abstract. Categories overlap, and a mention is not the same as testing the peptide as a treatment. Each number opens the exact PubMed search. Effects seen in laboratory or animal studies may not occur in humans. A registered clinical trial does not show that a substance is effective or safe.

Latest publications

Source: PubMed (NCBI) · verified October 30, 2026

Clinical trials

Registered
2
Active
0
With posted results
0

Conditions studied

  • Esophageal Varices 1
  • Portal Hypertension 1
  • Gastric Varices 1
  • Esophageal Bleeding 1
  • Pancreatic Cancer 1
  • Perioperative/Postoperative Complications 1
Study Status Phase Start
Use of Sanvar® With Endoscopic Treatment for the Control of Acute Variceal Bleeding
NCT00331188 Debiovision
Completed Phase 3 May 2006
Vapreotide in Treating Patients Undergoing Elective Pancreatic Resection
NCT00014651 Mayo Clinic
Terminated Phase 3 Mar 2001

All 2 studies on ClinicalTrials.gov ↗

Source: ClinicalTrials.gov · verified October 30, 2026

Adverse event reports

Reports
1
Serious
0
With death outcome
0

Most reported reactions

  • Pruritus generalised 1
  • Rash maculo-papular 1

Adverse event reports do not prove that the substance caused these effects. Side effects not listed here may still occur. Reaction terms are MedDRA terms as reported to FAERS.

Source: FDA FAERS (FAERS data as of July 30, 2026) · verified October 30, 2026 · API query

Change history

No changes since monitoring began on October 30, 2026.